Coenzyme Q10 is present in almost all the cells in our body and in lipoproteins. Practically every cell has the ability to synthesize Coenzyme Q10 but production starts to decrease in our 20s. The endogenous synthesis of CoQ10 happens to be a very complex process requiring numerous vitamins such as vitamin B6, vitamin B12, folic acid, niacinamide, pantothenic acid and vitamin C, and also certain trace elements. The quinone ring structure is derived from the amino acid tyrosine, the methyl groups on the ring supplied by methionine, and the isoprenoid side chain coming from the mevalonate pathway (the same pathway shared by cholesterol). Thus the production of CoQ10 is dependent on an adequate supply of numerous precursors and cofactors, and a deficiency of one or more of these essential components can adversely affect the production of adequate amounts of CoQ10.
Absorb Science’s Coenzyme Q10 is made by fermentation process. Commercially there is also a semisynthetic process for producing CoQ10 using Solanesol, a tobacco byproduct.
Fermented Coenzyme Q10 is a fat-soluble substance and therefore is absorbed like any other fat in our diet. In the small intestine, secretions from the pancreas and bile facilitate emulsification and micelle formation that are required for the absorption of fats along the small intestine. Once CoQ10 is taken up by the intestinal mucosal cells, it is transported via the lymphatic system as part of the chylomicrons and eventually taken up by the liver for repackaging into lipoprotein particles and re-released into the circulation.
The primary function of CoQ10 in our body is in cellular energy production. It is a critical component of mitochondria that are present in practically every cell in our body. It is in the Mitochondria that biological energy called ATP (adenosine triphosphate) is produced. CoQ10 is also a potent antioxidant and it helps protect the tissues and the cellular components in the body from free radical damage, and is vital for individuals taking statins as their CoQ10 drop during their course of Statin intake.
Recommended Dose: Adult (19 years & over) Take one softgel 1- 2 times per day with meals.